At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.Are you looking to make a significant difference by contributing to large molecule drug discovery?In This Role, You WillWe are seeking an ambitious post-doctoral scientist with strong research and communication skills to contribute to high visible research projects. Your work will contribute to the building structural mass spectrometry capabilities to support antibody discovery for multispan membrane protein targets.
- Develop cross linking (XL) and covalent labelling mass spectrometry (CLMS) based methods to study multispan membrane target interactions in a cellular environment.
- Evaluate different crosslinkers and their suitability to mapping epitopes of soluble protein targets.
- Develop diethylpyrocarbonate (DEPC) based or similar CLMS methods to study protein: antibody and protein/ protein interaction.
- Apply optimized CLMS and XLMS methods directly in cells.
- Expand applicability of these methods to multispan membrane targets to determine epitopes and protein interaction landscape.
- Working environment:
- Self-directed and highly motivated individual who can quickly identify key strategies and resources to accomplish research goals.
- Ability to work in a creative, fast-paced and cross functional team.
- Position requires the ability to partner with mass spectrometry, membrane protein antibody discovery and protein characterization teams across Lilly.
- Present findings at conferences and publish in high quality peer-reviewed journals.
Basic Qualifications
- PhD in Chemistry or related field with experience in protein mass spectrometry.
Additional Information
- This position is not permanent. It is for a fixed duration of two years with potential to extend to 3 years and for maximum of up to 4 years. You will have opportunities to apply for full time positions after your duration is complete.
Additional Skills/PreferencesIf you are described with these skills, you could be a great fit for the role:
- Experience with peptide mapping and analysis is preferred.
- Experience with Thermo and Waters mass spectrometry instrumentation is preferred.
- Experience with cell culture, membrane proteins and protein biochemistry will be beneficial.
- Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.
- Excellent communicator (oral and written) with presentation experience, along with a strong publication record.
- Proficient in data analysis and reporting
About Eli Lilly’s Postdoctoral Scientist ProgramWhen it comes to research and development, our goal is to discover and deliver innovative medicines that make life better for people around the world. It’s challenging, expensive and often filled with failure. But even when we fail, we advance medical science and understanding by learning more about diseases, biology and chemistry – ultimately bringing new solutions one step closer to reality.Over the course of our history, we have shed light on some of the toughest health care problems known to man – diabetes, heart disease, infectious diseases, neuroscience disorders, cancer and more. We could not pursue this without our research and development team.Postdoctoral scientists help us continue this pursuit. During your experience you will get:
- Top industry research experience
- Mentoring by some of Lilly’s top scientists
- Laboratory and classroom training and education to further your development
- Collaboration and networking across dozens of postdoctoral scientists and other researchers
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.
